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. 2015 Jul 15;10(3):030801. doi: 10.1116/1.4922798

Fig. 2.

Fig. 2.

Examples of cell mimic strategies. (a) Cancer cell membrane coated nanoparticles prepared through hypotonic and disruption technique. These coated particles retained the source cell's associated antigens and found applications in delivering tumor-associated antigens to APCs or homotypically targeting cancer cells. Reprinted with permission from Fang et al., Nano Lett. 14, 2181 (2014). Copyright 2014, American Chemical Society. (b) Nanoghosts prepared from MSCs through hypotonic treatment and homogenization. They exhibit MSC surface molecules, targeting abilities and are capable of inducing cancer cell death when loaded with a drug. Reprinted with permission from Toledano Furman et al. Nano Lett. 13, 3248 (2013). Copyright 2013, American Chemical Society. (c) Un-natural killer cells were prepared by functionalizing leukocytes with liposomes coated with E-selectin and TRAIL. They induced apoptosis of circulating cancer cells by activating the death receptor, TRAIL. Reprinted with permission from Mitchell et al., Proc. Natl. Acad. Sci. 111, 930 (2014). Copyright 2014, National Academy of Sciences.