Table 1. Results of antigen marker expression based on IHC for MCTS from two different glioma cell lines (U87 and U251) treated with invasion inhibitors.
Marker | U87 | U251 | ||||
---|---|---|---|---|---|---|
Control | LiCl | BIO | Control | LiCl | BIO | |
Cleaved caspase-3 | + 1 | + 1 | + 2 | + 2 | + 1 | + 3 |
Nestin | + 4 | + 4 | + 4 | + 4 | + 4 | + 4 |
SOX2 | + 4 | + 4 | + 4 | + 4 | + 2 | + 3 |
The remaining antigens (cleaved caspase 3, nestin and SOX-2) are discretely grouped into quartiles according to proportion of specimen stained (0=No cells stained; +4=76–100% cells stained)