Table 7.
Significantly depleted human TFs for the downregulated genes in the EMT process. The depleted transcription factors (TFs) were inferred by comparing ChIP-Seq or ChIP-chip identified target genes (TGs) of each TF with the downregulated genes in the EMT process. The depleted TFs were sorted according to the depleted fold ratios
Human TFs | PMID | # total TGs | # DETGs | Fold ratio | corrected P-value | Cell Lines |
---|---|---|---|---|---|---|
GABP | 17652178 | 655 | 16 | 3.5 | 2.8E-09 | JURKAT |
KDM6A | 18722178 | 410 | 14 | 2.5 | 2.2E-03 | U937_AND_SAOS2 |
ETS1 | 20019798 | 1446 | 59 | 2.1 | 3.3E-10 | JURKAT |
EST1 | 17652178 | 636 | 28 | 2 | 3.3E-03 | JURKAT |
GABP | 19822575 | 2430 | 132 | 1.6 | 4.4E-08 | HepG2 |
PMID pubmed article number; # total TGs number of ChIP-Seq or ChIP-chip identified target genes (TGs) of each TF; #DETGs number of differentially expressed genes