Table 2.

Mean cytokine concentration (pg/mL) (±SEM) in the ipsilateral L4-L5 DRG seven days following CCI

Cytokine	Sham (n = 5)	Combined CCI (n = 14)	Pain and disability (n = 5)	Pain and transient disability (n = 4)	Pain alone (n = 5)
IL-1β	65.3 ± 10.4	98.9 ± 8.8	102.1 ± 16.6	111.1 ± 24.9	86.0 ± 6.1
IL-6	35.7 ± 6.8	82.5 ± 4.7***	90.2 ± 9.9***	78.9 ± 12.4	77.5 ± 2.2
IL-10	255.4 ± 44.3	251.1 ± 18.0	217.2 ± 21.0	310.6 ± 34.2	237.4 ± 31.6
IL-17A	98.6 ± 17.0	89.0 ± 6.6	77.3 ± 5.0	106.7 ± 18.1	86.5 ± 10.6
IL-18	117.6 ± 13.6	108.1 ± 4.9	98.7 ± 6.9	123.5 ± 9.7	105.1 ± 7.5
TNF	30.0 ± 3.2	28.7 ± 1.3	27.4 ± 2.2	30.9 ± 2.8	28.3 ± 2.4
IFN-γ	47.1 ± 10.8	46.7 ± 4.9	42.2 ± 6.0	56.7 ± 13.6	43.1 ± 5.1
MCP-1	83.1 ± 4.0	149.0 ± 7.6***	152.1 ± 21.9**	136.8 ± 7.8	155.4 ± 3.8**

Statistically significant differences compared to sham are indicated by *P <0.05, **P <0.01 and ***P <0.001. All significant differences have been corrected for family-wise error rate with the Benjamini-Hochberg procedure, with a false discovery rate of q <0.05