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. 2015 Jul 3;6:7616. doi: 10.1038/ncomms8616

Figure 1. Challenges for asymmetric synthesis of N-allylic indoles.

Figure 1

(a) Selected examples of biologically active N α-chiral indoles. (b) Selectivity issue for allylation of indoles. (c) Strategies for transition metal-catalysed asymmetric synthesis of N-allylic indoles. LG, leaving group; EWG, electron-withdrawing group; FI, Fischer indolization.