Table 5.
Host and bacterium variables associated with gastric cancer (n = 232) in comparison with H. pylori-positive blood donors (n = 370)
| Covariate | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| p | OR | 95 % CI | p | |
| Age | < 0.001 | 1.20 | 1.16 - 1.23 | < 0.001 |
| Gender | < 0.001 | 2.99 | 1.48 - 6 | 0.002 |
| rs744166 | 0.002 | 1.76 | 1.14 - 2.70 | 0.01 |
| CagA +ve | < 0.001 | 12.80 | 5.48 - 29.86 | < 0.001 |
The Hosmer-Lemeshow test showed good fit (10 steps; 8 degrees of freedom; p = 0.20). rs744166 genotype was treated as categorical variables having 3 values with 0 meaning the AA genotype, 1 the carrier of one G allele and 2 the GG genotype, +ve, positive