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Effect of YL529 on tumor growth and survival in s. c. model. The mice bearing tumors subcutaneously were treated with YL529 or controls orally. a YL529 resulting in significant tumor growth inhibition; b Recovered tumor weights were significantly smaller in YL529 treated animals; c There was no significant difference of body weight after YL529 treated; d A significant increase in survival in YL529 treated mice was observed (Log-rank). Mean ± SEM, n = 10, *p < 0.05, **p < 0.01
