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. 2015 Jul 18;15:525. doi: 10.1186/s12885-015-1451-2

Table 1.

Pharmacokinetic parameters of YL529 after oral administration with single dose of 150 mg/kg in mice

Pharmacokinetic parameter Value
AUC(0-∞)(mg/L*h) 170.95
AUC(0-t)(mg/L*h) 167.32
t1/2β(h) 6.03
T1/2α(h) 1.39
t1/2z(h) 4.11
Cmax(mg/L) 18.03
Tmax(h) 2.00

Data were expressed as the mean ± SD compared with vehicle. SPSS (SPSS, IL) software was used for statistical analysis (n = 3; *p < 0.05)