Table 2.
The organs parameters of YL529 after oral administration 6000 mg/kg YL529 with a single dose in SD rats
| Index | Vehicle | YL529 | Vehicle | YL529 |
|---|---|---|---|---|
| Female(♀) | Female (♀) | Male (♂) | Male (♂) | |
| Heart (%) | 0.41 ± 0.08 | 0.42 ± 0.09 | 0.43 ± 0.05 | 0.42 ± 0.06 |
| Liver (%) | 3.11 ± 0.10 | 3.13 ± 0.09 | 3.09 ± 0.10 | 3.09 ± 0.13 |
| Spleen (%) | 0.23 ± 0.03 | 0.25 ± 0.03 | 0.23 ± 0.09 | 0.24 ± 0.04 |
| Lung (%) | 0.43 ± 0.05 | 0.43 ± 0.06 | 0.44 ± 0.11 | 0.42 ± 0.09 |
| Kidney (%) | 0.37 ± 0.06 | 0.38 ± 0.09 | 0.36 ± 0.08 | 0.38 ± 0.09 |
Data were expressed as the mean ± SD compared with vehicle. SPSS (SPSS, IL) software was used for statistical analysis (n = 10; *p < 0.05)