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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Adv Drug Deliv Rev. 2015 May 27;88:108–122. doi: 10.1016/j.addr.2015.05.014

Figure 2.

Figure 2

Strategies of miRNA inhibition therapy. Anti-miRs contain sequences that are complementary to the miRNA mature strands and act as competitive inhibitors. MiRNA sponges are DNA sequences with multiple binding sites to the miRNA. They could inhibit a panel of miRNAs. MiRNA masks could selectively block specific mRNA pathway.