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. Author manuscript; available in PMC: 2016 Jul 16.
Published in final edited form as: Mol Cell. 2015 Jul 2;59(2):176–187. doi: 10.1016/j.molcel.2015.05.032

Figure 1. Enhancement of miBRCA2 activity by DSS1.

Figure 1

See also Figure S1.

(A) Schematic of BRCA2 and miBRCA2 with various functional domains.

(B) SDS-PAGE of purified miBRCA2 (lane 1) and miBRCA2-DSS1 complex (lane 3). Size markers were run in lane 2.

(C) Schematic of the homologous DNA pairing reaction.

(D) The miBRCA2-DSS1 complex or miBRCA2 without and with DSS1 tested in homologous pairing reactions with ssDNA coated with RPA or SSB. The mean values (± s.d.) of data from 3 independent experiments were plotted.