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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Occup Environ Med. 2015 Feb 9;72(8):546–552. doi: 10.1136/oemed-2014-102579

Table 3.

Factors modifying FEV1 change (in mL) after work cessation based on a linear mixed effects model, with exposure modelled as cotton vs. silk.

FEV1, mL [95% CI]
All Non-smokers
Cessation-years 14.2*** [12.0, 16.5] 9.4*** [7.1, 11.7]
Cessation-years2 0.3*** [0.1, 0.4] 0.3*** [0.2, 0.5]
Cotton*cessation-years −2.7* [−5.0, −0.5] −1.7a [−4.2, 0.7]
Current smoker*cessation-years 1.1 [−2.6, 4.9] - -
Former smoker*cessation-years 0.4 [−4.4, 5.2] - -
Male*cessation-years −5.7** [−9.1, −2.3] −4.5** [−7.8, −1.3]

Observations 4,702 3,068
*

p<0.05

**

p<0.01

***

p<0.001

Note: Quadratic interaction terms were significant only for the male*cessation-years2 term, with β=0.5 [0.2, 0.8], p=0.0009 for all workers and β=0.4 [0.1, 0.7], p=0.02 for the analysis restricted to non-smokers.

a

cotton*cessation-years interaction p=0.08 in analysis restricted to non-smokers

Model adjusted for age, height, gender, exposure (cotton vs. silk), smoking (never, current, former), cumulative pack-years, and interaction terms between cessation-years and occupational exposure, cessation-years and smoking, and cessation-years and gender. Loss-to follow-up accounted for using inverse probability of censoring weights. Note: as the modelled outcome was FEV1 and not change in FEV1, the interaction terms with cessation-years represent the associations between occupational exposure, smoking, gender, and change in FEV1 after leaving work.