Table 4.
Seventy-tree proteins identified exclusively in pancreatic cancer specimens and not in the other two cohorts, as illustrated in the Venn diagram in Figure 2.
| Name | UniProt ID | Spectral counts |
No. of specimens in which a protein was identified |
|||
|---|---|---|---|---|---|---|
| PC#1 | PC#2 | PC#3 | Mean | |||
| 14-3-3 protein epsilon | P62258 | 0 | 31 | 0 | 10 | 1 |
| 40S ribosomal protein S18 | P62269 | 0 | 27 | 0 | 9 | 1 |
| 40S ribosomal protein S24 | P62847 | 15 | 49 | 0 | 21 | 2 |
| 40S ribosomal protein S3 | P23396 | 0 | 27 | 0 | 9 | 1 |
| 40S ribosomal protein SA | P08865 | 20 | 25 | 0 | 15 | 2 |
| 60S acidic ribosomal protein P0 | P05388 | 0 | 40 | 0 | 13 | 1 |
| 60S acidic ribosomal protein P2 | P05387 | 0 | 4 | 0 | 1 | 1 |
| 60S ribosomal protein L37a | P61513 | 24 | 0 | 0 | 8 | 1 |
| Acyl-coenzyme A synthetase ACSM6, mitochondrial | Q6P461 | 18 | 0 | 0 | 6 | 1 |
| Aldehyde dehydrogenase family 16 member A1 | Q8IZ83 | 24 | 0 | 0 | 8 | 1 |
| Aldehyde dehydrogenase, mitochondrial | P05091 | 22 | 0 | 0 | 7 | 1 |
| Alpha-1-acid glycoprotein 1 | P02763 | 0 | 0 | 12 | 4 | 1 |
| Alpha-1-antichymotrypsin | P01011 | 0 | 0 | 16 | 5 | 1 |
| Anterior gradient protein 2 homolog | O95994 | 16 | 0 | 0 | 5 | 1 |
| Anterior gradient protein 3 homolog | Q8TD06 | 0 | 0 | 5 | 2 | 1 |
| Apolipoprotein E | P02649 | 0 | 0 | 28 | 9 | 1 |
| Azurocidin | P20160 | 27 | 29 | 0 | 19 | 2 |
| Band 4.1-like protein 2 | O43491 | 31 | 0 | 0 | 10 | 1 |
| Carcinoembryonic antigen-related cell adhesion molecule 5 | P06731 | 0 | 0 | 16 | 5 | 1 |
| Catalase | P04040 | 13 | 0 | 0 | 4 | 1 |
| Catenin alpha-2 | P26232 | 67 | 0 | 0 | 22 | 1 |
| Chymotrypsin-C | Q99895 | 0 | 13 | 0 | 4 | 1 |
| Complement C4-A | P0C0L4 | 0 | 0 | 56 | 19 | 1 |
| Complement component C9 | P02748 | 0 | 0 | 21 | 7 | 1 |
| Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 1 | P04843 | 0 | 47 | 0 | 16 | 1 |
| ELAV-like protein 1 | Q15717 | 24 | 0 | 0 | 8 | 1 |
| Epiplakin | P58107 | 165 | 0 | 171 | 112 | 2 |
| Erythrocyte band 7 integral membrane protein | P27105 | 0 | 0 | 28 | 9 | 1 |
| Fatty acid synthase | P49327 | 45 | 0 | 0 | 15 | 1 |
| Fatty acid-binding protein, liver | P07148 | 13 | 0 | 0 | 4 | 1 |
| Filamin-B | O75369 | 51 | 0 | 0 | 17 | 1 |
| Heat shock protein HSP 90-beta | P08238 | 62 | 0 | 0 | 21 | 1 |
| Heterogeneous nuclear ribonucleoprotein Q | O60506 | 0 | 51 | 0 | 17 | 1 |
| Heterogeneous nuclear ribonucleoproteins C1/C2 | P07910 | 29 | 0 | 0 | 10 | 1 |
| Histone H2A type 2-A | Q6FI13 | 0 | 87 | 0 | 29 | 1 |
| Histone H2A.Z | P0C0S5 | 34 | 0 | 0 | 11 | 1 |
| Histone H2B type 1-O | P23527 | 140 | 0 | 0 | 47 | 1 |
| Histone H2B type 2-F | Q5QNW6 | 0 | 0 | 185 | 62 | 1 |
| HLA class I histocompatibility antigen, Cw-7 alpha chain | P10321 | 22 | 0 | 0 | 7 | 1 |
| HLA class II histocompatibility antigen, DRB1-9 beta chain | Q9TQE0 | 15 | 0 | 0 | 5 | 1 |
| IgGFc-binding protein | Q9Y6R7 | 42 | 0 | 0 | 14 | 1 |
| Importin subunit beta-1 | Q14974 | 22 | 0 | 0 | 7 | 1 |
| Integrin alpha-M | P11215 | 0 | 0 | 68 | 23 | 1 |
| Keratin, type I cuticular Ha6 | O76013 | 31 | 0 | 0 | 10 | 1 |
| Keratin, type I cytoskeletal 16 | P08779 | 53 | 0 | 0 | 18 | 1 |
| Keratin, type II cuticular Hb5 | P78386 | 33 | 0 | 0 | 11 | 1 |
| Keratin, type II cytoskeletal 7 | P08729 | 83 | 60 | 105 | 83 | 3 |
| Lactotransferrin | P02788 | 22 | 0 | 37 | 20 | 2 |
| L-lactate dehydrogenase A chain | P00338 | 25 | 0 | 30 | 18 | 2 |
| Mucin-2 | Q02817 | 34 | 0 | 0 | 11 | 1 |
| Mucin-5B | Q9HC84 | 0 | 0 | 91 | 30 | 1 |
| Myeloblastin | P24158 | 18 | 0 | 9 | 9 | 2 |
| Myosin-14 | Q7Z406 | 123 | 0 | 0 | 41 | 1 |
| Nicotinate phosphoribosyltransferase | Q6XQN6 | 7 | 0 | 0 | 2 | 1 |
| Outer dense fiber protein 3 | Q96PU9 | 0 | 0 | 14 | 5 | 1 |
| PDZ and LIM domain protein 1 | O00151 | 18 | 0 | 0 | 6 | 1 |
| Phenylalanine-tRNA ligase alpha chain | Q9Y285 | 0 | 22 | 0 | 7 | 1 |
| Protein disulfide-isomerase A3 | P30101 | 31 | 47 | 0 | 26 | 2 |
| Protein DJ-1 | Q99497 | 0 | 27 | 0 | 9 | 1 |
| Protein S100-A8 | P05109 | 0 | 0 | 9 | 3 | 1 |
| Proteolipid protein 2 | Q04941 | 0 | 4 | 0 | 1 | 1 |
| Putative trypsin-6 | Q8NHM4 | 0 | 0 | 47 | 16 | 1 |
| Retinal dehydrogenase 1 | P00352 | 0 | 31 | 0 | 10 | 1 |
| Solute carrier family 12 member 2 | P55011 | 51 | 0 | 0 | 17 | 1 |
| Spectrin beta chain, brain 1 | Q01082 | 71 | 0 | 0 | 24 | 1 |
| Staphylococcal nuclease domain-containing protein 1 | Q7KZF4 | 0 | 65 | 0 | 22 | 1 |
| Superoxide dismutase | P00441 | 9 | 0 | 0 | 3 | 1 |
| Translocon-associated protein subunit delta | P51571 | 0 | 9 | 0 | 3 | 1 |
| Transthyretin | P02766 | 0 | 0 | 9 | 3 | 1 |
| Tripeptidyl-peptidase 1 | O14773 | 11 | 0 | 19 | 10 | 2 |
| Trypsin-3 | P35030 | 0 | 63 | 0 | 21 | 1 |
| Tubulin beta-4B chain | P68371 | 45 | 25 | 0 | 23 | 2 |
| Tubulin-specific chaperone A | O75347 | 9 | 0 | 0 | 3 | 1 |
PC: pancreatic cancer