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. Author manuscript; available in PMC: 2016 Jan 15.
Published in final edited form as: Cancer Res. 2015 May 14;75(14):2811–2821. doi: 10.1158/0008-5472.CAN-14-3761

Fig.2. Adenovirus causes rapid cytokine induction in murine tissues.

Fig.2

Female CD1nu/nu mice with intraperitoneal SKOV3ip1 tumours were injected IP with dl922-947 (1010 particles). Samples were analysed in triplicate and data are presented as mean±SD (n=3-4).

A. Cytokine protein in murine serum using mouse and human specific plates shown relative to 0 hours. Mouse and human cytokines are compared (p<0.05, **p<0.01, ***p<0.001). hpi=hours post-infection.

B. qRT-PCR analysis of tumour. Expression at 1, 3, 6 and 24 hours is shown relative to expression at 0 hours. Mouse and human cytokines are compared (*p<0.05, **p<0.01, ***p<0.001). hpi=hours post-infection.

C+D qRT-PCR analysis of spleen (C) and liver (D). Cytokines at 1, 3, 6 and 24 hours are shown relative to 0 hours post IP dl922-947.