Table 3.

Associations between composite genetic risk score and prior cardiovascular disease (CVD), prior myocardial infarction (MI), and coronary artery calcification in the DHS were assessed using marginal models with generalized estimating equations. Associations between the composite genetic risk score and all-cause and CVD mortality were assessed using Cox proportional hazards models. Models were adjusted for age and sex.

Trait	β Estimate/Odds or Hazard Ratio	95% Confidence Interval		p-value
Self-reported history of MI *	1.01	1.00	1.02	0.149
Self-reported history of CVD *	1.00	0.99	1.01	0.481
Coronary artery calcification †	0.021	0.010	0.031	1.23 × 10−4
All-cause mortality ‡	1.00	0.99	1.01	0.919
CVD mortality ‡	1.00	0.99	1.01	0.718

^*Calculated using marginal models with generalized estimating equations, odds ratios shown

^†calculated using marginal models with generalized estimating equations, β estimates shown

^‡Calculated using Cox proportional hazards models, hazard ratios shown