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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2015 Feb 27;1854(9):1184–1193. doi: 10.1016/j.bbapap.2015.02.013

FIGURE 1.

FIGURE 1

Cysteine biosynthesis in bacteria: the role of CysK, its reaction mechanism and the role of reaction intermediates in gene regulation. Closed grey arrow represents inhibition of transcription, open grey arrow represents activation of transcription. Closed symbols represent fully active enzymes, open symbols represent inhibited enzymes. OAS spontaneously converts to NAS with a pH dependent rate that is 1%/min at pH 7.6 [45].