Table 3.

Association of dementia severity with informal costs of dementia care since dementia onset

	Mini Mental State Exam (MMSE) Model				Clinical Dementia Rating Scale Model
	N = 279 (580)†				N = 284 (603)†
Variable	Unadjusted‡		Adjusted‡		Unadjusted‡		Adjusted‡
	expβ	95% CI	expβ	95% CI	expβ	95% CI	expβ	95% CI
Time in years	1.070	1.015 1.127	1.084	1.027 1.143	1.051	0.985 1.120	1.050	0.987 1.116
Dementia Severity
MMSE (Time-varying)	0.932	0.913 0.951	0.940	0.922 0.960
CDR (Time-varying)
Categorical, vs. Very mild
Mild					2.958	1.764 4.961	2.690	1.725 4.194
Moderate					5.466	3.397 8.797	4.998	3.231 7.730
Severe					7.288	4.252 12.489	6.318	3.733 10.692
Less than HS education (vs. completed HS/GED)			0.497	0.339 0.729			**
Any vascular dementia (vs. no vascular dementia)			0.519	0.370 0.729			0.480	0.355 0.650
NPI			1.019	1.006 1.032
Good/Excellent GMHR (vs. poor/fair)			0.652	0.441 0.964			0.734	0.532 1.012

^*Models adjusted for: age at dementia onset, gender, apoe4, general medical health rating (GMHR), education, type of dementia, and neuropsychiatric inventory (NPI); non-significant covariates were removed from the model, often to help models converge.

^†The potential sample for each analysis was N = 287 subjects (with 611 observations), however some observations were unable to be included in the analysis due to missing variable(s).

^‡Multivariable mixed models using GEE with gamma distribution and log link.

^**Model did not converge with inclusion of this covariate.