Table 3.
Adjusted Odds Ratios (ORs) and their corresponding 95% confidence intervals (CIs) for the association of ALS with insulin-dependent and non-insulin-dependent diabetes mellitus.
| No diabetes | Insulin-dependent diabetes | Non-insulin-dependent diabetes | |
|---|---|---|---|
| ALS cases, n (%) | 4,863 (97.1) | 43 (0.9) | 104 (2.1) |
| Controls, n (%) | 24,059 (95.8) | 259 (1.0) | 785 (3.1) |
| ORa (95%CI) | 1.00 (Ref) | 0.83 (0.60–1.15) | 0.66 (0.53–0.81) |
| ORa by Age at the index date (years) | |||
| <50 | 1.00 (Ref) | 5.38 (1.87–15.51) | 2.12 (0.37–12.10) |
| 50–59 | 1.00 (Ref) | 1.16 (0.54–2.51) | 0.77 (0.32–1.83) |
| 60–69 | 1.00 (Ref) | 1.19 (0.65–2.19) | 0.74 (0.49–1.12) |
| 70–79 | 1.00 (Ref) | 0.45 (0.25–0.82) | 0.67 (0.49–0.91) |
| 80 and above | 1.00 (Ref) | 0.46 (0.14–1.51) | 0.51 (0.33–0.80) |
a
OR adjusted for sex, age, area of residence, education and socioeconomic status; 136 cases and 767 controls with missing information on education and socioeconomic status were excluded in this analysis.