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Target hepatic lesion in a 65-year-old man treated with sorafenib: Clinical example of responder on dynamic contrast-enhanced ultrasound. A: Contrast-enhanced ultrasound with corresponding time-intensity curve at baseline; B: Fifteen days after onset of sorafenib therapy, contrast-enhanced ultrasound revealed an increase in tumour necrosis with drastic reduction of tumour perfusion parameters shown by contrast enhancement pattern and corresponding time-intensity curve.
