Table 2.
Condition | Component | Regions (BA) | x | y | z | Δr | P value | P-FDR corrected |
---|---|---|---|---|---|---|---|---|
Component of interest | IC1: visual component | R inferior occipital gyrus (BA 18) | 24 | −96 | 3 | |||
L inferior occipital gyrus (BA 18) | −30 | −90 | −9 | |||||
Children with RD Test 1 < TR Test 1 | IC1 and IC2: executive functions | R superior frontal gyrus (BA 8) | 18 | 39 | 51 | 0.16 | 0.02 | 0.05 |
L superior frontal gyrus (BA 8) | −21 | 39 | 51 | |||||
L middle frontal gyrus (BA 6) | −33 | 18 | 57 | |||||
R middle frontal gyrus (BA 6) | 36 | 18 | 57 | |||||
IC1 and IC3: attention | L anterior cingulate gyrus (BA 24) | 0 | 33 | 18 | 0.13 | 0.05 | 0.11 | |
R anterior cingulate gyrus (BA 24) | 3 | 30 | 18 | |||||
L insula (BA 13) | −42 | 3 | 15 | |||||
R insula (BA 13) | 42 | 12 | 18 | |||||
IC1 and IC4: sensory–motor | R precentral gyrus (BA 5) | 30 | −36 | 57 | 0.17 | 0.01 | 0.05 | |
L precentral gyrus (BA 5) | −30 | −36 | 57 | |||||
R paracentral gyrus (BA 5) | 3 | −36 | 54 | |||||
L paracentral gyrus (BA 5) | −3 | −36 | 54 | |||||
L cingulate (BA 31) | 0 | −36 | 36 | |||||
Children with RD Test 2 > TR Test 2 | IC1 and IC5: language | R inferior frontal gyrus (BA 9) | 51 | 15 | 27 | 0.18 | 0.02 | 0.11 |
L inferior frontal gyrus (BA 9) | −48 | 15 | 27 | |||||
L middle frontal gyrus (BA 8) | −48 | 24 | 30 | |||||
L anterior cingulate gyrus (BA 24) | −3 | 0 | 30 | |||||
L precuneus (BA 19) | −33 | −63 | 48 | |||||
Children with RD Test 2 > children with RD Test 1 | IC1 and IC6: the OT stream | R lingual gyrus (BA 18) | 18 | −87 | −12 | .2 | 0.02 | 0.04 |
L lingual gyrus (BA 18) | −15 | −90 | −12 | |||||
R inferior temporal gyrus (BA 20) | 60 | −54 | −15 | |||||
L cuneus (BA 17) | 0 | −96 | 6 | |||||
L inferior occipital gyrus (BA 17) | −15 | −96 | −6 | |||||
IC1 and IC7: dorsal attention | R precuneus (BA 7) | 3 | −60 | 45 | 0.19 | 0.001 | 0.02 | |
L precuneus (BA 7) | −3 | −60 | 45 | |||||
R superior frontal gyrus (BA 9) | 6 | 57 | 24 | |||||
Left superior temporal gyrus (BA 39) | −54 | −60 | 24 | |||||
R angular gyrus (BA 39) | 57 | −54 | 24 | |||||
IC1 and IC8: memory | L parahippocampal gyrus (BA 35) | −27 | −27 | −24 | 0.23 | 0.01 | 0.03 | |
R parahippocampal gyrus (BA 35) | 30 | 6 | −21 | |||||
IC1 and IC2: executive functions | See above | 0.16 | 0.05 | 0.09 | ||||
TR Test 2 < TR Test1 | IC1 and IC5: language | See above | 0.12 | 0.03 | 0.24 |
The results of the difference in correlation coefficients between the component of interest (IC1) and the other components (IC2–8) between the different conditions are noted in the right columns (Δr = correlation coefficient value, P = significance without correction for multiple comparisons, FDR = significance with false discovery rate correction for multiple comparisons). All results were corrected for multiple comparisons using false discovery rate (FDR).
BA, Brodmann area; IC, independent components; RD, children with reading difficulty; TR, typical readers; L, left; R, right; OT, occipito-temporal.