Table 3.

Summary of miRNA and chemosensitivity

miRNA and chemosensitivity		Summary
Micro RNA	Ref.
miR-21	[65-68]	Increased expression causes decreased chemosensitivity
miR-153	[69]	Up regulation, increased resistance to oxaliplatin and cisplatin
miR-19a	[70]	Up regulation leads to resistance of FOLFOX therapy
miR-106a	[71]	Up regulation leads to resistance of 5-FU and oxalilatin
miR-130b	[71]	Up regulation leads to resistance of 5-FU and oxalilatin
miR-484	[71]	Up regulation leads to resistance of 5-FU and oxalilatin
miR-129	[72]	Down regulation increases resistance to 5-FU, transfection of miRNA into existing cells increase cytotoxic effect 5-FU
miR-15b	[73]	Down regulation increases resistance to 5-FU
miR-1915	[74]	Down regulation decreases chemotherapy by modulating apoptotic pathway
miR-122	[75]	Down regulation increases resistant to 5-FU

5-FU: 5-fluorouracil.