Table 3.
Regression coefficients and integer risk scores of acute-on-chronic liver failure predictors estimated from the derivation set
| ACLF predictors | Regression coefficient | P value | Risk score |
| Age ≥ 40 (yr) | 1.128 | 0.010 | 1 |
| TBil ≥ 171 (μmol/L) | 1.237 | 0.007 | 1 |
| PTA (%) | |||
| 50.1-60 | 2.158 | 0.001 | 2 |
| 40-50 | 2.868 | < 0.001 | 3 |
| HBV DNA > 107 (copies/mL) | 1.946 | < 0.001 | 2 |
| Overall risk level | ACLF rate | Total score | |
| Low risk | 0%-4.7% | 0-3 | |
| High risk | 26.0%-68.8% | 4-7 |
The regression coefficient 1.128 is considered as one risk point. ACLF: Acute-on-chronic liver failure; HBV: Hepatitis V virus; PTA: Prothrombin activity; TBil: Total bilirubin.