FIG. 3.

Masson trichrome staining showing stromal scar development at 1 week (A), 4 weeks (B), and 8 weeks (C) postpolymer scaffold implantation (Scale bars: 500 μm). Uninjured spinal cord tissue is designated with a diamond, fibrinoid scar with an arrow, and collagen scar with an arrowhead. The fragments of OPF+ scaffold material were present in all sections. The mounting process floated them to different positions but this did not interfere with measurements. Quantification of collagen scar area (D) and fibrinoid scar area (E) over time in animals implanted with scaffolds containing Schwann cells or Matrigel only. p<0.05 for main effect of time postimplantation for collagen and fibrinoid scar areas. Color images available online at www.liebertpub.com/tea