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. 2015 Jun 4;172(14):3565–3578. doi: 10.1111/bph.13146

Figure 2.

Figure 2

Effect of EGCG and its derivatives on the sub-G1 population and apoptotic protein expression in K562 cells. (A) Effect of EGCG and its derivatives on the apoptotic sub-G1 population of K562 cells. Cells were treated with EGCG and its derivatives at 30 μM for 24 h, stained with PI and the cell cycle analysed by flow cytometry. Data are presented as means ± SD. **P < 0.01, significantly different from untreated controls. (B) Effects of EGCG and its derivatives on caspase 9/3 and PARP in K562 cells. K562 cells were treated with EGCG (30 and 100 μM), EGCG-MO, EGCG-ML and EGCG-MP (30 μM) for 24 h. Cell lysates were prepared and analysed by Western blotting for caspase 9, cleaved caspase 3 and PARP.