Table 1. Multivariate analysis of risk factors related to OS and recurrence of HCC patients.
| Variable | HR | 95% CI | p |
|---|---|---|---|
| OS | |||
| AFP, ng/mL | |||
| ≤20 | 1 | ||
| >20 | 1.58 | 1.17–2.13 | .003 |
| Cirrhosis | |||
| no | 1 | ||
| yes | 1.66 | 1.10–2.49 | .016 |
| GGT, U/L | |||
| ≤50 | 1 | ||
| >50 | 1.35 | 1.01–1.81 | .045 |
| Tumor size, cm | |||
| ≤5 | 1 | ||
| >5 | 1.58 | 1.19–2.09 | .001 |
| Vascular invasion | |||
| no | 1 | ||
| yes | 1.66 | 1.23–2.46 | .001 |
| Tumor number | |||
| single | 1 | ||
| multiple | 1.68 | 1.23–2.30 | .001 |
| TMPRSS4 expression | |||
| Negative | 1 | ||
| Positive | 2.20 | 1.66–2.90 | <.001 |
| Recurrence | |||
| GGT, U/L | |||
| ≤50 | 1 | ||
| >50 | 1.53 | 1.13–2.07 | .006 |
| Vascular invasion | |||
| no | 1 | ||
| yes | 1.40 | 1.00–1.95 | .050 |
| Tumor number | |||
| single | 1 | ||
| multiple | 1.89 | 1.34–2.67 | <.001 |
| TMPRSS4 expression | |||
| Negative | 1 | ||
| Positive | 1.95 | 1.45–2.63 | <.001 |
Overall survival: OS; Hazard Ratio: HR; Confidence Interval: CI; γ—glutamyltransferase: GGT; AFP: a-fetoprotein; TMPRSS4: transmembrane serine protease 4.