. 2015 Jun 29;112(28):8726–8731. doi: 10.1073/pnas.1501029112

Table S1.

STAT3 DNA-binding consensus sequences are found in the human and murine EDNRB promoter

Binding motif	Species	(ID), sequence, and promoter position in bp
TTC(N)₄GAA	Human	(A) `TTCATTTGAA`, −1,175
TTC(N)₄GAA	Mouse	(A) `TTCATGGGAA,` −1,512
TTM(N)₃DAA	Human	(1) `TTCCCCAAA,` −3,012
		(2) `TTACAATAA`, −2,971
		(3) `TTAAGTGAA`, −2,875
		(4) `TTACCTTAA,` −2,695
		(5) `TTATAAAAA,` −2,609
		(6) `TTCCATTAA`, −1,904
		(7) `TTACCTGAA`, −1,298
		(8) `TTAAAAAAA`, −688
		(9) `TTACGTGAA`, −320
	Mouse	(1) `TTAAAAAAA`, −2,973
		(2) `TTCCCCAAA`, −973
		(3) `TTAGTAAAA`, −330
		(4) `TTAGCTAAA`, −155

Promoter sites in mouse and human satisfying STAT3-binding motifs TTM(N)3DAA (D: A, G, or T; M: A or C; N: A, G, T, or C) or TTC(N)4GAA (N: A, G, T or C). Positions are relative to the transcriptional start sequence for transcript variant 1 in both human and mouse EDNRB. Human EDNRB sequence data were obtained from GenBank accession ID NG_011630 (www.ncbi.nlm.nih.gov/genbank/) with the transcriptional start point (position 0) located at 61,797 bp in sequence context. Mouse EDNRB sequence data were obtained from GenBank accession ID NC_000080.6 with the transcriptional start point located at 5,254 bp in sequence context.