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Disruption of intestinal HIF-2α results in maternal anemia. (A) Serum iron of HIF-2αF/F and HIF-2αIntKO mice at day 18 of pregnancy and at 1 d postpartum. (B) Liver iron of HIF-2αF/F and HIF-2αIntKO mice at 1 day postpartum. (C) Red blood cells (RBCs), hemoglobin (Hb), and hematocrit (HCT) levels of HIF-2αF/F and HIF-2αIntKO mice at day 18 of pregnancy and at 1 d postpartum. Each bar represents the mean value ± SEM *P < 0.05 vs. HIF-2αF/F.
