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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Immunol. 2015 Aug 1;195(3):780–788. doi: 10.4049/jimmunol.1500909

Figure 1. Adaptive and Innate Immune Responses to C. albicans.

Figure 1

C. albicans exists in various morphologies, which are sensed by PRRs such as C-type lectin receptors found on APCs as well as epithelial cells. Exposure to C. albicans induces expression of innate cytokines, many of which are inductive for IL-17-expression cells. Various sources of IL-17 are documented in the context of candidiasis, including innate and adaptive cell types. IL-17 signaling on epithelial or other non-hematopoietic cells leads to expression of chemokines, AMPs and other factors that contribute to fungal control.