Table 3.
Dimethyl phthalate | Diethyl phthalate | Dibutyl phthalate | Butylbenzyl phthalate | Di(2-ethylhexyl) phthalate | ||||||
---|---|---|---|---|---|---|---|---|---|---|
β | 95% CI | β | 95% CI | β | 95% CI | β | 95% CI | β | 95% CI | |
ASD and DD children (n = 77) | ||||||||||
Mullen (DQ scores) | ||||||||||
Composite score | 0.60 | [−3.3; 4.5] | 0.97 | [−3.8; 5.7] | 0.13 | [−6.1; 6.4] | −2.20 | [−6.1; 1.7] | 0.30 | [−6.2; 6.8] |
Expressive language | 0.22 | [−4.3; 4.8] | 1.44 | [−4.2; 7.1] | −0.11 | [−7.5; 7.3] | −2.90 | [−7.5; 1.7] | −1.52 | [−9.2; 6.1] |
Fine motor | 0.76 | [−2.5; 4.0] | 0.02 | [−4.1; 4.1] | −2.60 | [−8.0; 2.8] | −1.70 | [−5.1; 1.7] | 0.64 | [−5.0; 6.2] |
Receptive language | 1.41 | [−3.2; 6.0] | 1.09 | [−4.6; 6.8] | −0.37 | [−7.8; 7.1] | −2.20 | [−6.9; 2.5] | 1.21 | [−6.5; 8.9] |
Visual reception | −0.01 | [−4.8; 4.8] | 1.34 | [−4.6; 7.3] | 3.61 | [−4.2; 11] | −2.00 | [−7.0; 3.0] | 0.89 | [−7.3; 9.0] |
Vinland (standard scores) | ||||||||||
Composite score | 0.29 | [−1.9; 2.5] | 0.37 | [−2.3; 3.0] | −0.22 | [−3.7; 3.3] | −0.40 | [−2.6; 1.8] | −2.00 | [−5.6; 1.6] |
Communication | −0.43 | [−2.8; 1.9] | −0.20 | [−3.1; 2.7] | −1.16 | [−4.9; 2.6] | −0.53 | [−2.9; 1.9] | −2.46 | [−6.3; 1.4] |
Daily living skills | 1.75 | [−0.5; 3.9] | 1.53 | [−1.3; 4.3] | 0.74 | [−3.0; 4.5] | 0.41 | [−1.9; 2.8] | 0.01 | [−3.8; 3.9] |
Motor skills | 0.14 | [−3.0; 3.3] | 2.08 | [−1.9; 6.0] | −2.25 | [−7.4; 2.9] | −1.34 | [−4.6; 2.0] | −4.40 | [−9.7; 0.9] |
Socialization | 0.18 | [−2.4; 2.8] | −0.72 | [−3.9; 2.5] | 2.25 | [−1.9; 6.4] | −0.63 | [−3.3; 2.0] | −0.32 | [−4.7; 4.0] |
TD children (n = 68) | ||||||||||
Mullen (DQ scores) | ||||||||||
Composite score | 0.83 | [−2.2; 3.9] | −1.83 | [−5.2; 1.5] | −0.38 | [−4.0; 3.3] | 0.96 | [−1.5; 3.4] | 1.78 | [−2.3; 5.9] |
Expressive language | −0.28 | [−4.2; 3.6] | −2.17 | [−6.8; 2.5] | 0.00 | [−5.0; 5.0] | 0.13 | [−3.3; 3.5] | 0.71 | [−4.9; 6.4] |
Fine motor | 1.90 | [−1.3; 5.1] | 1.06 | [−2.5; 4.7] | 1.01 | [−2.9; 4.9] | 1.05 | [−1.6; 3.7] | 3.48 | [−0.8; 7.8] |
Receptive language | 0.63 | [−3.4; 4.6] | −2.70 | [−7.3; 1.8] | −0.64 | [−5.6; 4.3] | 0.98 | [−2.4; 4.3] | 1.41 | [−4.2; 7.0] |
Visual reception | 1.04 | [−3.4; 5.5] | −3.50 | [−8.2; 1.2] | −1.90 | [−7.0; 3.3] | 1.67 | [−1.8; 5.1] | 1.52 | [−4.3; 7.4] |
Vinland (standard score) | ||||||||||
Composite score | 1.19 | [−2.4; 4.8] | −4.45 | [−8.2; −0.7] | −3.56 | [−7.6; 0.5] | 0.43 | [−2.4; 3.3] | −0.08 | [−4.8; 4.6] |
Communication | 0.39 | [−2.7; 3.5] | −4.38 | [−7.6; −1.2] | −3.77 | [−7.3; −0.3] | −0.46 | [−2.9; 2.0] | −1.29 | [−5.4; 2.8] |
Daily living skills | 1.43 | [−1.8; 4.6] | −3.29 | [−6.8; 0.3] | −3.16 | [−7.0; 0.7] | 0.14 | [−2.5; 2.8] | −1.37 | [−5.8; 3.0] |
Motor skills | 1.56 | [−1.8; 4.9] | −2.06 | [−5.6; 1.5] | −1.71 | [−5.6; 2.2] | 0.58 | [−2.0; 3.2] | 1.36 | [−3.0; 5.8] |
Socialization | 0.15 | [−2.8; 3.1] | −2.90 | [−6.0; 0.3] | −1.36 | [−4.8; 2.1] | 1.28 | [−1.1; 3.6] | 1.24 | [−2.7; 5.2] |
Analyses adjusted for child age at assessment, child gender and race, maternal education and date of dust collection
ASD autism spectrum disorder, DD developmental delay, TD typically developing
aDate of dust collection was missing for one participant