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. 2015 Jun 24;30(8):1952–1963. doi: 10.1093/humrep/dev124

Table V.

Risk of colorectal and thyroid cancer for ART women compared with non-ART women, stratified analyses.

Colorectal cancer (C18-20)
Thyroid cancer (C73)
ART Non-ART HR Lower bound Upper bound ART Non-ART HR Lower bound Upper bound
n n n n
Number of cancers during the observational period 25 1364 13 919
Crude risk 22 1364 1.36 0.89 2.07 13 919 1.14 0.66 1.97
Adjusted riska 22 1364 1.31 0.85 2.01 13 919 1.15 0.66 2.00
Excl. cancer during the first yearb 22 1354 1.34 0.87 2.06 13 894 1.18 0.68 2.06
Parity at entry
 P0 20 659 1.43 0.91 2.25 12 640 1.07 0.60 1.91
 P1+ 2 705 0.90 0.22 3.60 1 279 0.97 0.13 6.93
 Total 22 1364 13 919
Parity at exit
 One 9 183 1.13 0.57 2.23 3 201 0.50 0.15 1.55
 Two 10 572 1.41 0.75 2.65 7 403 1.59 0.75 3.39
 Three or more 3 609 1.81 0.58 5.64 3 315 2.60 0.83 8.15
 Total 22 1364 13 919
Method of ART
 IVF 16 1364 1.27 0.77 2.10 9 919 1.15 0.59 2.23
 ICSI 2 1364 0.95 0.24 3.80 2 919 0.87 0.22 3.51
 Other 4 1364 1.86 0.69 4.98 2 919 1.59 0.40 6.40
 Total 22 13
Duration of follow-up, years
 <1 year 0 10 NA 0 26 NA
 1–5 6 81 2.27 0.96 5.41 3 186 0.82 0.26 2.61
 >5–10 5 158 1.13 0.46 2.82 3 238 0.81 0.26 2.58
 >10 11 1115 1.16 0.64 2.12 7 469 1.84 0.87 3.93
 Total 22 1364 13 919

aHazard ratios are adjusted for attained age, age at start of follow-up, parity, region of residence and calendar period.

bThose with an index cancer diagnosed within the first year of follow-up were omitted from this analysis.