Alignment of PpaA/AerR peptide sequences that were characterized for cobalamin binding in this study with that of AppA. The conserved cobalamin-binding motif is highlighted in red. Rs, R. sphaeroides; Js, Jannaschia sp. strain CCS1; Me, M. extorquens; Rc, R. centenum; Rg, R. gelatinosus; Rp, R. palustris; Eb, Erythrobacter sp. strain NAP1; Rca, R. capsulatus.