Table 3. Multivariate negative binomial regression on epilepsy incidence and prevalence*.
Independent variable | Incidence | Prevalence | |||
---|---|---|---|---|---|
IRR (95% CI) | p-value | OR (95% CI) | p-value | ||
Age (vs. 65-74 y/o) | 75-84 y/o | 0.64 (0.50-0.82) | <0.001 | 0.61 (0.54-0.70) | <0.001 |
85+ y/o | 0.43 (0.31-0.60) | 0.33 (0.27-0.40) | |||
Male (vs. female) | 1.05 (0.84-1.33) | 0.652 | 1.13 (1.00-1.28) | 0.045 | |
Race (vs. non-Hispanic whites) | Hispanics | 0.91 (0.70-1.18) | 0.452 | 0.86 (0.74-0.99) | 0.003 |
Non-Hispanic blacks | 1.28 (0.78-2.08) | 1.33 (1.03-1.72) | |||
Non-Hispanic others | 0.85 (0.62-1.17) | 1.10 (0.94-1.29) | |||
Location (vs. rural-rural counties) | Urban-rural counties | 1.54 (1.01-2.37) | 0.128 | 0.85 (0.65-1.11) | 0.419 |
Urban-urban counties | 1.04 (0.82-1.32) | 0.94 (0.83-1.07) | |||
Married (vs. not) | 0.88 (0.69-1.13) | 0.332 | 0.85 (0.74-0.98) | 0.021 | |
Anoxic brain injury (vs. not) | 7.37 (1.73-31.40) | 0.007 | 1.69 (0.82-3.45) | 0.153 | |
Stroke (vs. not) | 4.65 (3.54-6.11) | <0.001 | 3.81 (3.34-4.33) | <0.001 | |
Atherosclerosis (vs. not) | 1.00 (0.74-1.35) | 0.998 | 1.18 (1.01-1.38) | 0.032 | |
Primary brain tumor (vs. not) | 11.12 (2.18-56.59) | 0.004 | 4.44 (2.14-9.20) | <0.001 | |
Alzheimer's disease (vs. not) | 2.25 (1.56-3.27) | <0.001 | 1.45 (1.20-1.76) | <0.001 | |
Parkinson's disease (vs. not) | 1.71 (0.99-2.97) | 0.057 | 1.69 (1.30-2.20) | <0.001 | |
Dementia (vs. not) | 2.04 (1.44-2.88) | <0.001 | 2.26 (1.90-2.69) | <0.001 | |
Hypertension (vs. not) | 2.86 (2.22-3.69) | <0.001 | 1.81 (1.58-2.07) | <0.001 | |
Sleep apnea (vs. not) | 1.34 (0.91-1.97) | 0.144 | 1.09 (0.88-1.35) | 0.431 |
*p-value of alpha (the overdispersion parameter) <0.001.
95% CI: 95 percent confidence interval, IRR: incidence rate ratio, OR: odds ratio, y/o: years old.