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. 2015 Jul 16;10(Suppl 1):117–123. doi: 10.4137/BMI.S20056

Figure 1.

Figure 1

Common mechanisms of damage to cells of the renal tubules and interstitium, together with examples of the toxicants that drive each type of damage. This diagram shows three of the four mechanisms described in the text: not shown, because of the scale of the diagram, is interference with vascular function, as caused by NSAIDS in patients with existing circulatory or renal problems.