. 2015 Jul 14;10:1313–1320. doi: 10.2147/COPD.S78180

Table 1.

Anthropometric and functional characteristics of 139 patients grouped according to GOLD spirometric grades

	All	GOLD grade			ANOVA P-value
	All	2	3	4	ANOVA P-value
N	139	46	56	37
Sex, M/F	134/5	46/0	53/3	35/2
Age (yr)	63±8	63±8	63±7	60±7	NS
BMI (m/kg2)	25±4	24±4	26±3	24±4	NS
FVC (% pred)	72±18	82±14	71±17^*	60±17^*,^≠	<0.001
FEV₁ (L)	1.3±0.6	1.9±0.5	1.2±0.2^*	0.7±0.2^*,^≠	<0.001
FEV₁ (% pred)	41±16	59±7	39±6^*	20±4^*,^≠	<0.001
FEV₁/FVC (%)	40±15	52±8	41±14^*	25±8^*,^≠	<0.001
TLC (% pred)	116±21	113±17	112±22	124±22^≠	0.004
RV (% pred)	200±75	156±44	191±69^*	266±68^*,^≠	<0.001
IC (% pred)	62±18	76±16	63±16^*	47±12^*,^≠	<0.001
RV/TLC (%)	61±11	52±8	59±9^*	71±8^*,^≠	<0.001
IC/TLC ratio	0.26±0.07	0.32±0.06	0.27±0.07^*	0.18±0.05^*,^≠	<0.001
DLco (% pred)	57±25	72±23	59±21^*	36±15^*,^≠	<0.001
PaO₂ (mmHg)	69±12	77±10	68±11^*	62±11^*,^≠	<0.001
PaCO₂ (mmHg)	40±6	37±4	41±6^*	45±7^*,^≠	<0.001
AaPO₂ (mmHg)	32±10	30±11	32±9	34±10	NS

Notes: Data are presented as means ± standard deviation. Significant differences within each variable are indicated as:

different from GOLD grade 2;

^≠

different from GOLD grade 3.

Abbreviations: AaPO₂, alveolar–arterial oxygen partial pressure difference; ANOVA, analysis of variance; BMI, body mass index; DLco, diffusing capacity for carbon dioxide; FEV₁, post-bronchodilator forced expiratory volume in 1 second; FEV₁/FVC, post-bronchodilator forced expiratory volume in 1 second/post-bronchodilator forced vital capacity; FVC, post-bronchodilator forced vital capacity; GOLD, Global Initiative for Chronic Obstructive Pulmonary Disease; IC, inspiratory capacity; IC/TLC, inspiratory capacity/total lung capacity ratio; M/F, male/female; NS, not significant; PaCO₂, partial pressure of arterial carbon dioxide; PaO₂, partial pressure of arterial oxygen; pred, predicted; RV, residual volume; RV/TLC, residual volume/total lung capacity ratio; TLC, total lung capacity.