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. Author manuscript; available in PMC: 2015 Jul 20.
Published in final edited form as: Adv Exp Med Biol. 2014;773:415–430. doi: 10.1007/978-1-4899-8032-8_19

Fig. 2.

Fig. 2

A summary of the p53, pRb, and apoptotic pathways known to modulate the levels of lamin expression in response to oxidative stress. Oxidative stress induces an increase in LA/C expression, a decrease in LB1 expression, but no change in the expression of LB2 through the p53 and pRb pathways. Lamin proteins can be cleaved by oxidative-stress induced apoptosis