Fig. 6.

Combined SPIO-based DOX delivery and SPIO-induced MFH. The viability of HeLa cells was determined following treatment with media alone, water bath heating (43°C), just PEG 2000 SPIO (without DOX), DOX-loaded PEG 2000 SPIOs, or free DOX. Each of the indicated groups had samples with or without a 1 hour exposure to an AMF (23.77 kA/m, 355 kHz). (A) Temperature profiles during AMF treatment of media, SPIO, DOX-SPIO samples. (B) Cell viability measured 24 hours after treatment using an MTT assay. Error bars represent standard error.