Table 1.

Basic information on candidate tSNPs analyzed in this study.

SNP ID	Gene	Position	Band	Base change	Role	MAF case	MAF control	pa value for HWE test	OR 95%CI	pb value
rs498872	PHLDB1	118477367	11q23.3	C/T	Downstream	0.264	0.276	0.80	0.94 (0.62–1.42)	0.76
rs980444	PLA2G4A	38167710	15q14	T/C		0.417	0.443	0.99	0.90 (0.62–1.30)	0.57
rs12439272	PLCB2	40584804	15q15.1	G/A	Intron	0.118	0.086	0.76	1.43 (0.80–2.55)	0.23
rs7003908	PRKDC	48770702	8q11.21	A/C	Intron	0.243	0.226	0.62	1.10 (0.72–1.68)	0.66
rs701848	PTEN	89726745	10q23.31	T/C	3′ UTR	0.444	0.409	0.91	1.16 (0.80–1.67)	0.44
rs2160138	RPA3	7755797	7p21.3	T/C	Intron	0.243	0.214	0.41	1.18 (0.77–1.81)	0.44
rs4140805	RPA3	7727101	7p21.3	T/G	Intron	0.229	0.208	0.42	1.13 (0.73–1.75)	0.57
rs6947203	RPA3	7737048	7p21.3	C/T	Intron	0.139	0.133	0.79	1.06 (0.62–1.79)	0.84
rs2297440	RTEL1	62312299	20q13.33	T/C	Intron	0.375	0.259	0.05	1.72 (1.17–2.52)	<0.01*
rs4809324	RTEL1	62318220	20q13.33	T/C	Intron	0.097	0.113	0.72	0.85 (0.46–1.55)	0.59
rs6010620	RTEL1	62309839	20q13.33	A/G	Intron	0.382	0.264	0.03	1.72 (1.18–2.52)	<0.01*
rs2072532	SLC8A1	40366301	2p22.1	T/C	Intron	0.167	0.205	1.00	0.78 (0.48–1.25)	0.3
rs2110922	SLC8A1	40363644	2p22.1	T/G	Intron	0.403	0.43	1.00	0.89 (0.62–1.29)	0.55
rs202445	SOD1	33025667	21q22.11	A/G	Promoter	0.021	0.012	0.99	1.80 (0.46–7.06)	0.65
rs2066804	STAT1/STAT4	191841759	2q32.2	C/T	Intron (boundary)	0.5	0.448	0.77	1.23 (0.86–1.77)	0.26
rs2853676	TERT	1288547	5p15.33	G/A	Intron	0.222	0.171	0.06	1.39 (0.89–2.17)	0.15
rs3755377	TGFA	70732852	2p13.3	C/T	Intron	0.417	0.457	0.21	0.85 (0.59–1.23)	0.38
rs1805015	IL4R	27374180	16p12.1	T/C	Coding exon	0.104	0.098	0.56	1.07 (0.59–1.95)	0.82
rs7989882	TNFRSF19	24214603	13q12.12	G/A	Intron	0.229	0.236	0.85	0.96 (0.63–1.48)	0.86
rs1042522	TP53	7579472	17p13.1	G/C	Coding exon	0.486	0.409	0.83	1.37 (0.95–1.97)	0.09
rs8079544	TP53	7580052	17p13.1	C/T	Intron	0.118	0.084	0.42	1.45 (0.81–2.60)	0.21
rs17748	TREH, PHLDB1	118528424	11q23.3	C/T	Downstream	0.229	0.271	0.14	0.80 (0.52–1.23)	0.31
rs3828550	KDR	55976451	4q12	C/T	Intron	0.299	0.318	0.49	0.91 (0.61–1.36)	0.65
rs861530	XRCC3	104174123	14q32.33	A/G	Intron	0.41	0.42	0.99	0.96 (0.66–1.39)	0.82
rs3212092	XRCC3	104168644	14q32.33	C/T	Intron	0.063	0.04	0.83	1.61 (0.73–3.55)	0.23
rs1056503	XRCC4	82648977	5q14.2	G/T	Coding exon	0.264	0.284	0.99	0.90 (0.60–1.36)	0.63
rs3770502	XRCC5	217045059	2q35	G/A	Intron	0.132	0.166	0.95	0.76 (0.45–1.29)	0.31
rs9288516	XRCC5	217053264	2q35	T/A	Intron	0.403	0.458	0.60	0.80 (0.55–1.15)	0.23
rs6519265	XRCC6	42025350	22q13.2	G/A	Intron	0.125	0.084	0.17	1.55 (0.88–2.74)	0.13

MAF – minor allele frequency; OR – odds ratio; 95% CI – 95% confidence interval. p^a<0.01 indicates statistical significance; p^b<0.05 indicates statistical significance for allele model.