Table 1.
HIV Infected and Uninfected Study Patients at Baseline
| HIV Infected (n=40,038) | Uninfected (n=79,039) | P value | ||
|---|---|---|---|---|
|
|
||||
| Age (years) | Mean (SD) | 46.3 (10.2) | 46.6(10.3) | <0.001 |
| Gender | Male | 39,102 (98%) | 77,185 (98%) | 0.951 |
| Race | White | 15,019 (38%) | 30,927 (39%) | <0.001 |
| African American | 19,340 (48%) | 36,978 (47%) | ||
| Hispanic | 2,985 (7.5%) | 6,019 (7.6%) | ||
| Other | 2,694 (6.7%) | 5,115 (6.5%) | ||
| Comorbidities | Alcohol abuse | 6,456 (16%) | 11,496 (15%) | <0.001 |
| Atrial fibrillation | 308 (0.8%) | 793 (1.0%) | <0.001 | |
| CAD | 1,422 (3.6%) | 4,861 (6.2%) | <0.001 | |
| Cancer | 2,035 (5.1%) | 2,554 (3.2%) | <0.001 | |
| CHF | 647 (1.6%) | 1,299 (1.6%) | 0.735 | |
| Cirrhosis | 418 (1.0%) | 474 (0.6%) | <0.001 | |
| COPD | 1,733 (4.3%) | 3,129 (4.0%) | 0.003 | |
| Depression, major | 2,651 (6.6%) | 4,625 (5.9%) | <0.001 | |
| Diabetes | 2,926 (7.3%) | 9,640 (12%) | <0.001 | |
| Drug abuse | 7,484 (19%) | 9,827 (12%) | <0.001 | |
| Hepatitis B, chronic | 1,191 (3.0%) | 302 (0.4%) | <0.001 | |
| Hepatitis C | 3,716 (9.3%) | 2,354 (3.0%) | <0.001 | |
| Hypertension | 7,020 (18%) | 21,039 (27%) | <0.001 | |
| Hyperlipidemia | 2,306 (5.8%) | 10,666 (13%) | <0.001 | |
| Osteoarthritis | 1,059 (2.6%) | 5,380 (6.8%) | <0.001 | |
| PTSD | 1,896 (4.7%) | 6,120 (7.7%) | <0.001 | |
| PVD | 412 (1.0%) | 1,050 (1.3%) | <0.001 | |
| Renal insufficiency | 1,621 (4.1%) | 1,325 (1.7%) | <0.001 | |
| Schizophrenia | 1,367 (3.4%) | 4,880 (6.2%) | <0.001 | |
| Stroke | 628 (1.6%) | 1,349 (1.7%) | 0.080 | |
| TIA | 75 (0.2%) | 181 (0.2%) | 0.146 | |
| cART | 20,997 (52%) | n/a | n/a | |
| BMI, kg/m2 | <18.5 | 2,464 (5.0%) | 1,052 (1.1%) | <0.001 |
| 18.5–24.9 | 19,834(48%) | 20,324 (22%) | ||
| 25–29.9 | 12,590 (33%) | 29,850 (37%) | ||
| ≥30 | 5,150 (14%) | 27,813 (40%) | ||
| Hemoglobin, g/dl | >12 | 30,658 (77%) | 72,920 (92%) | <0.001 |
| 10–12 | 6,393 (16%) | 4,660 (5.9%) | ||
| <10 | 2,987 (7.5%) | 1,458 (1.9%) | ||
| Albumin, g/dl | ≥3.5 | 27,393 (68%) | 69,499 (88%) | <0.001 |
| <3.5 | 12,645 (32%) | 9,540 (12%) | ||
| CD4 cell count, cells/mm3 | ≥ 500 | 9,748 (24%) | n/a | n/a |
| 350 – 499 | 7,303 (18%) | n/a | ||
| 200 – 349 | 8,640 (22%) | n/a | ||
| 50 – 199 | 8,807 (22%) | n/a | ||
| <50 | 5,540 (14%) | n/a | ||
| Viral load, copies/ml | <500 | 11,154 (28%) | n/a | n/a |
| ≥ 500 | 28,884 (72%) | n/a | ||
SD = Standard deviation; CAD = Coronary artery disease; CHF = Congestive heart failure; COPD = chronic obstructive pulmonary disease; PTSD = post-traumatic stress disorder; PVD = peripheral vascular disease; TIA = Transient ischemic attack
cART = Combination anti-retroviral therapy
BMI = Body mass index