Skip to main content
. 2015 Jul 20;10(7):e0132496. doi: 10.1371/journal.pone.0132496

Fig 2. Nuclear factor (NF)–kB p65 subunit activity in monocytes from cancer patients with and without DVT and effect of DHMEQ.

Fig 2

The activated NF-kB p65 subunit was significantly higher in cancer patients DVT+ and DVT- than in healthy controls (P< 0.0001). (ANOVA test). NF-kB p65 subunit was significantly higher in cancer patients DVT+ than in those DVT- (P< 0.001) (t-test). To examine the effects of DHMEQ, monocytes were treated with 10 μg/mL DHMEQ. As control experiments, DMSO was used instead of DHMEQ. Monocytes from cancer patients DVT+ were more responsive to DHMEQ than those from DVT-. Intriguingly, no effect of DHMEQ there was in healthy monocytes. The results are shown as the means ± SD. OD, optical density; DVT, Deep Vein thrombosis; DMSO, dimethyl sulfoxide; DHEMQ, dehydroxymethylepoxyquinomicin.