Table 5. Serum-depend activation of NF-kB regulated markers production from healthy monocytes.

HM, Monocytes from healthy subjects; sH, sera from healthy subjects; LPS, lipopolysaccharide; sCaDVT-, serum from cancer patients without deep venous thrombosis; sCADVT+, serum from cancer patients with deep venous thrombosis; IL-6, Interleukin-6; TNF- α, Tumor necrosis factor alpha; IL-1β, Interleukin-1 beta; VEGF, Vascular endothelial growth factor; MMP-9, matrix metalloproteinase-9; TF, Tissue factor. All p values were calculated by Wilcoxon Matched-Pairs Signed-Ranks Test.

	HM	HM + sH	P value°	HM + sCaDVT-	HM + sCaDVT+	P value*
IL-6	21.1 ± 6.1	21 ± 7.1	ns	66.4 ± 25.4	82.3 ± 25.9	0.01
TNF-α	30.3 ± 9.4	29.2 ± 9.2	ns	121 ± 44.2	143 ± 43.6	0.01
IL-1β	15 ± 5.1	14 ± 5.9	ns	80.2 ± 27.2	111 ± 34.9	0.01
VEGF	42 ± 12.8	36 ± 11.6	ns	98.8 ± 17.6	121 ± 28.7	0.01
MMP-9	8.8 ± 3.7	9.4 ± 4.9	ns	58.4 ± 12.4	70.9 ± 17	0.01
TF	2.7 ± 0.8	2.5 ± 0.5	ns	57.2 ± 14.7	85.4 ± 18.6	0.01

(°) p value calculated between HM and (HM+sH)

(*) p value calculated between (HM + sCaDVT-) and (HM + sCaDVT+).