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5-HT2A receptor agonists increase respiratory rate and minute ventilation without much effect on tidal volume in Lmx1bf/f/p mice. Bar graphs depict effect of DOI (left) and TCB-2 (right) on breathing frequency (A and B), tidal volume (C and D), and minute ventilation (E and F). Values are means ± SE; n = 6 for each drug and dose. All data are normalized to baseline. *P < 0.05 with respect to baseline.
