Fig. 7.
Heterogeneous responses of dorsal horn projection neurons to SCS were also present in animals following constriction injury (CCI). A: CCI produced a significant reduction in paw withdrawal thresholds (n = 8; P < 9.5 × 10−7, Student's t-test). B: representative brush-sensitive WDR neuron, brush-insensitive WDR neuron, and NS neuron indicating that neurons are responsive to stimulation of the peripheral receptive field following CCI. C: normalized responses from 6 responsive projection neurons out of 7 neurons found from CCI animals. C, insets: results of least squares regression classification of the frequency-response curves plotted against the original classification scheme (Fig. 6). Data from one nonresponsive neuron are not shown.