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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Environ Sci Nano. 2014 Nov 10;2(1):33–53. doi: 10.1039/C4EN00138A

Figure 2.

Figure 2

Citrate-EDTA stabilized nanoparticles exhibit a relatively lengthy half-life and can penetrate the blood brain barrier. (A) Sprague Dawley rats were injected intravenously with 10 mg/kg Nanoceria, and the blood ceria content was measured by ICP-MS over time. (B–E) Healthy SJL/J mice were injected once intravenously with 20 mg/kg Nanoceria, and tissues were harvested at various time points to assess ceria content by ICP-MS. The amount of ceria in each tissue at 24 hours post-injection is indicated as “Load”.