Table 1.

Some of the features of the studied miRNAs

miRNA	Rationale for inclusion in the current study	Previous studies’ findings	References
miR18a-5p	Believed to be involved in DNA damage in OCD	Altered in DNA damage response	24
miR22-3p	Believed to regulate four candidate genes: BDNF, MAOA	Found to be altered in panic disorder	25
miR24-3p	Believed to be related to oxidative stress, which is a potential neurobiological mechanism in OCD	Found to be altered in oxidative DNA damage and lipid peroxidation	26
miR106b-5p	Believed to be related to oxidative stress, which is a potential neurobiological mechanism in OCD	Downregulated in resveratrol treatment that has antioxidant properties	27
miR107	Believed to be related to minimal brain change in OCD	Altered in traumatic brain injury and neurodegenerative diseases	28
miR125b-5p	Believed to be related to hypoxia in OCD	Altered in high altitude sickness	29
miR155a-5p	Believed to be related to inflammation which is a potential neurobiological mechanism in OCD	Altered in inflammation	30

Abbreviations: BDNF, brain-derived neurotrophic factor; OCD, obsessive–compulsive disorder.