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. 2015 Jul 20;10(7):e0133580. doi: 10.1371/journal.pone.0133580

Table 3. Multivariable linear regression for the associations between FGF23 concentrations and the best subset of FGF23 correlates, mutually adjusted for each other.

Whole study population Exclusion eGFR < 60 mL/min/1.73m2
Parameter β coefficient (95% CI) P value a β coefficient (95% CI) P value a
n = 2134 n = 2061
Men -0.21 (-0.28;-0.14) <0.001 -0.22 (-0.30;-0.15) <0.001
Physical activity, Q2 -0.0004 (-0.07;0.07) 0.99 -0.003 (-0.07;0.07) 0.93
Physical activity, Q3 -0.01 (-0.08;0.07) 0.89 -0.01 (-0.08;0.07) 0.89
Physical activity, Q4 0.07 (-0.01;0.15) 0.08 0.08 (-0.01;0.16) 0.07
Smokers 0.12 (0.06;0.18) <0.001 0.12 (0.06;0.19) <0.001
PTH, pg/mL b 0.13 (0.08;0.17) <0.001 0.13 (0.08;0.16) <0.001
Creatinine, mg/dL b 0.28 (0.14;0.41) <0.001 0.27 (0.11;0.43) 0.001
Total cholesterol, mg/dL 0.001 (0.00003;0.001) 0.04 0.001 (0.0001;0.001) 0.01
HDL-cholesterol, mg/dL -0.002 (-0.003;-0.0001) 0.06 -0.002 (-0.003;-0.0001) 0.04
C-reactive protein, mg/dL b 0.03 (0.01;0.05) 0.01 0.02 (-0.001;0.04) 0.07
Total protein intake, Q2 0.04 (-0.04;0.11) 0.37 0.02 (-0.06;0.10) 0.63
Total protein intake, Q3 -0.03 (-0.11;0.06) 0.41 -0.05 (-0.13;0.03) 0.21
Total protein intake, Q4 -0.04 (-0.12;0.05) 0.42 -0.05 (-0.15;0.04) 0.23
Calcium intake, mg/dL b 0.10 (0.03;0.18) 0.01 0.04 (-0.07;0.15) 0.45
Iron intake, mg/d b -0.25 (-0.42;-0.08) 0.005 -0.29 (-0.47;-0.12) 0.001
Alcohol intake, g/d b -0.02 (-0.04;-0.002) 0.03 -0.02 (-0.04;-0.001) 0.07
Energy intake, kcal/d b 0.25 (0.08;0.42) 0.003 0.21 (0.01;0.40) 0.03

eGFR stands for estimated glomerular filtration rate; Q2, Q3, Q4 stand for quartile 2, 3 and 4.

a Based on mutual adjustment.

b Natural log transformed.