Table 3. Top functional gene groupings activated in WT-TAC but not AKAP13-ΔPKD1 TAC hearts.
| Molecular and Cellular Functions | p-value Range | No. Genes |
|---|---|---|
| Cell Death and Survival | 2.73x10-7–1.69x10-2 | 92 |
| Drug Metabolism | 7.91x10-7–1.68x10-2 | 112 |
| Protein Synthesis | 7.91x10-7–1.67x10-2 | 66 |
| Cellular Development | 2.65x10-6–1.69x10-2 | 78 |
| Cellular Growth and Proliferation | 9.41x10-6–1.59x10-2 | 98 |
| Physiological Systems Development and Function | ||
| Organ Morphology | 9.41x10-6–1.59x10-2 | 63 |
| Skeletal and Muscular System Development and Function | 5.05x10-6–1.67x10-2 | 52 |
| Cardiovascular System Development and Function | 1.20x10-5–1.63x10-2 | 63 |
| Tissue Morphology | 1.94x10-5–1.53x10-2 | 36 |
| Hepatic System Development and Function | 1.94x10-5–1.53x10-2 | 26 |
| Diseases and Disorders | ||
| Neurological Disease | 2.73x10-7–1.69x10-2 | 92 |
| Cancer | 7.91x10-6–1.68x10-2 | 112 |
| Gastrointestinal Disease | 7.91x10-7–1.67x10-2 | 66 |
| Psychological Disorders | 2.65x10-6–1.59x10-2 | 78 |
| Skeletal and Muscular Disorders | 9.41x10-6–1.59x10-2 | 98 |