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(a) Time evolutions for the deviation of hTRPV1 bound with AMG9810 (antagonist, highlighted in black color) and bound with RTX (agonist, highlighted in red color) during 50 ns MD simulations, (b) calculated RMSF of Cα atoms vs protein residue number for hTRPV1 bound with AMG9810 (antagonist, highlighted in black color) and bound with RTX (agonist, highlighted in red color).
