Table 2.
Peripheral blood engraftment levels in recipients of daughter cells 12 weeks after BMT |
Bone marrow engraftment levels in secondary recipients of daughter cells 6 months after BMT |
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---|---|---|---|---|---|---|---|---|---|---|
Genotype | Total daughter cells injected |
# Of mice with > 1% engraftment |
Individual mouse information |
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Total engraftment level (%) |
Multi-lineage analysis (%) |
Total engraftment level (%) |
Multi-lineage analysis (%) |
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T | B | M | ||||||||
p18+/+ | 64 | 2 | 2.68 | 81.6 | 13.3 | 5.2 | NA | NA | ||
2.07 | 17.3 | 61.4 | 21.4 | NA | NA | |||||
p18−/− | 64 | 5 | 77.90 (9,437*) | 35.5 | 44.8 | 19.7 | 9.44 (from 9,437*, n=3) | 74.83 | 20.52 | 4.65 |
13.52 (9,625*) | 91.9 | 6.3 | 1.8 | 5.20 (from 9,625*, n=2) | 98.92 | 0.36 | 0.72 | |||
9.71 (9,640*) | 63.6 | 36.0 | 0.4 | 2.90 (from 9,640*, n=2) | 96.59 | 1.28 | 2.30 | |||
4.04 (9,671*) | 5.3 | 27.7 | 67.0 | NA (from 9,671*) | NA | |||||
1.51 (9,386*) | 7.4 | 72.6 | 19.9 | 0.61 (from 9,386*, n=1) | 93.22 | 3.41 | 3.38 |
BMT, bone marrow transplantation; NA, not applicable;
ID number of mouse.