Skip to main content
. 2014 Feb 18;18(6):1060–1070. doi: 10.1111/jcmm.12250

Figure 5.

Figure 5

Current traces and statistical analysis show the effects of the Ca2+/CaM pathway on melatonin (MT)-induced inhibition of INa in extremely low-frequency electromagnetic field (ELF-EMF)-exposed cerebellar granule cells. (A) Representative superimposed INa traces and statistical analysis showing that KN-93 significantly abolished the effect of MT on the EMF-induced INa increase. (B) Representative superimposed INa traces and statistical analysis showed that C6-ceremade (C6) could mimic the effect of MT on the EMF-induced INa increase. (C) Representative superimposed INa traces and statistical analysis showed that ruthenium red (Rud) significantly abolished the effect of MT on the EMF-induced INa increase. *P < 0.05 compared with the non-ELF-EMF-exposed controls using Student's t-test. #P < 0.05 compared with the corresponding control (ELF-EMF exposed to MT) using Student's t-test. †P < 0.05 compared with the corresponding control without C6-ceramide treatment using Student's t-test.