Table 2.
Odds Ratios (95% CIs) for Association of Erectile Dysfunction With Undiagnosed Hypertension, Hypercholesterolemia, and Diabetes Among Men Aged ≥20 Years in NHANES 2001–2004
| Undiagnosed Hypertension (n=2,224) | Undiagnosed Hypercholesterolemia (n=2,287) | Undiagnosed Diabetes (n=1,417) | ||||
|---|---|---|---|---|---|---|
|
|
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| Characteristic | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) |
| Erectile dysfunction | 2.35 (1.78–3.11) | 1.27 (0.87–1.85) | 0.73 (0.47–1.15) | 0.67 (0.42–1.07) | 4.58 (2.54–8.24) | 2.20 (1.10–4.37)a |
| Age-group, y | ||||||
| 20–39 (ref) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| 40–59 | 2.47 (1.69–3.61) | 2.38 (1.55–3.66)a | 1.88 (1.25–2.84) | 1.84 (1.24–2.75)a | 8.24 (2.49–27.19) | 5.56 (1.78–17.35)a |
| ≥60 | 7.29 (4.90–10.84) | 7.41 (4.43–12.37)a | 1.12 (0.76–1.65) | 1.45 (0.87–2.43) | 14.83 (5.19–42.34) | 8.70 (2.91–26.03)a |
| Ethnicity | ||||||
| Non-Hispanic white (ref) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Non-Hispanic black | 1.47 (1.07–2.02) | 1.99 (1.34–2.97)a | 0.76 (0.47–1.23) | 0.87 (0.54–1.40) | 0.78 (0.39–1.56) | 1.25 (0.57–2.71) |
| Mexican American | 0.64 (0.41–0.98) | 0.90 (0.60–1.35) | 0.92 (0.64–1.31) | 0.97 (0.65–1.46) | 0.25 (0.11–0.58) | 0.53 (0.21–1.33) |
| Other | 0.66 (0.34–1.30) | 0.92 (0.46–1.85) | 1.13 (0.64–1.99) | 1.37 (0.77–2.44) | 1.21 (0.46–3.15) | 2.39 (0.87–6.55) |
| Physically active | 0.99 (0.77–1.28) | 0.84 (0.62–1.13) | 0.82 (0.59–1.14) | 0.84 (0.60–1.18) | 0.70 (0.33–1.47) | 0.73 (0.35–1.55) |
| Alcohol use | ||||||
| Never (ref) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Former | 1.57 (0.78–3.17) | 1.31 (0.53–3.25) | 1.28 (0.54–3.04) | 0.90 (0.36–2.26) | 1.73 (0.56–5.36) | 1.42 (0.47–4.30) |
| Current | 0.85 (0.47–1.51) | 0.95 (0.44–2.06) | 3.12 (1.57–6.21) | 2.48 (1.20–5.10)a | 0.62 (0.23–1.68) | 0.67 (0.29–1.55) |
| Current smoker | 0.65 (0.43–0.98) | 0.82 (0.50–1.32) | 1.59 (1.16–2.18) | 1.65 (1.17–2.32)a | 0.57 (0.25–1.34) | 1.00 (0.41–2.41) |
| History of hypertension | n/ab | n/ab | 1.10 (0.72–1.68) | 0.95 (0.56–1.61) | 3.88 (2.16–6.96) | 1.83 (0.92–3.65) |
| History of high cholesterol | 1.21 (0.87–1.68) | 0.71 (0.48–1.05) | n/ab | n/ab | 2.89 (1.68–4.98) | 1.55 (0.81–2.99) |
| History of diabetes | 0.96 (0.46–1.98) | 0.56 (0.28–1.14) | 0.54 (0.27–1.08) | 0.45 (0.21–0.97)a | n/ab | n/ab |
| History of cardiovascular disease | 1.11 (0.45–2.74) | 0.59 (0.20–1.76) | 1.20 (0.62–2.33) | 1.24 (0.60–2.59) | 1.48 (0.71–3.07) | 0.46 (0.18–1.17) |
| Family history of hypertension/stroke | 0.90 (0.60–1.35) | 1.22 (0.76–1.95) | 0.75 (0.53–1.06) | 0.68 (0.47–0.99)a | 0.93 (0.54–1.62) | 0.96 (0.54–1.72) |
| Family history of angina/heart attack | 0.59 (0.38–0.92) | 0.68 (0.41–1.13) | 1.12 (0.71–1.78) | 1.18 (0.74–1.90) | 1.36 (0.65–2.86) | 1.26 (0.50–3.14) |
| Family history of diabetes | 0.93 (0.74–1.18) | 1.02 (0.78–1.32) | 1.33 (0.95–1.87) | 1.30 (0.92–1.84) | 2.24 (1.40–3.59) | 2.35 (1.50–3.68)a |
| Weight status | ||||||
| Normal weight/underweight (ref) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Overweight | 2.10 (1.45–3.04) | 1.75 (1.15–2.67)a | 2.23 (1.51–3.30) | 2.17 (1.46–3.23)a | 2.83 (0.74–10.81) | 2.28 (0.74–6.99) |
| Obese | 3.11 (2.18–4.46) | 2.37 (1.64–3.43)a | 2.79 (1.70–4.58) | 2.74 (1.68–4.47)a | 5.98 (1.69–21.10) | 3.60 (1.30–9.93)a |
n/a = not applicable; NHANES = National Health and Nutrition Examination Survey; OR = odds ratio; ref = reference group.
a
Statistically significant (P <.05).
b
Men with previous history excluded.